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Search Results for " peptidase inhibitor 4 "
Targets Recommended: DPP-4

41

抑制剂 & 化合物

2

天然产物

41

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Cat. No. Product Name Target Signaling Pathways
T11526 DPP-IV-IN-2

H-Lys(4-nitro-Z)-pyrrolidide

DPP-4 Proteases/Proteasome
DPP-IV-IN-2 (H-Lys(4-nitro-Z)-pyrrolidide) 是二肽基肽酶 IV 和DP8/9的抑制剂, IC50分别为 0.1 和 0.95 μM。
T6192 Alogliptin

SYR-322,阿格列汀,阿洛利停

Ferroptosis; Proteasome; DPP-4 Apoptosis; Proteases/Proteasome; Ubiquitination
Alogliptin (SYR-322) 是一种具有选择性口服活性的DPP-4的抑制剂,IC50值小于 10 nM,比对 DPP-8 和 DPP-9 的抑制性高 10000 倍以上,可研究 2 型糖尿病。
T7369L Gemigliptin Tartrate(911637-19-9 free base)

吉格列汀酒石酸盐,LC15-0444 tartrate

Proteasome; DPP-4 Proteases/Proteasome; Ubiquitination
Gemigliptin Tartrate (LC15-0444 tartrate) 是一种选择性的,可逆的,竞争性的二肽基肽酶 4 (DPP-4) 抑制剂,对于人重组 DPP-4 的IC50=10.3 nM。Gemigliptin tartrate 具有很强的抗糖基化活性,能够用于晚期糖基化终产物相关的糖尿病并发症的研究。
T12710 Retagliptin Phosphate

SP 2086,瑞格列汀磷酸盐

Proteasome; DPP-4 Proteases/Proteasome; Ubiquitination
Retagliptin Phosphate (SP 2086) 是一种选择性、竞争性、口服活性的二肽基肽酶 4 (DPP-4) 抑制剂。Retagliptin phosphate 能够用于 2 型糖尿病 (T2DM) 的研究。
T7133 Anagliptin

SK-0403,阿拉格列汀

Proteasome; DPP-4 Proteases/Proteasome; Ubiquitination
Anagliptin (SK-0403) 是一种选择性的二肽酰肽酶 4 抑制剂,IC50=3.8 nM,对 DPP-8/9 的选择性相对较弱,IC50分别为 68 和 60 nM。
T2401 Alogliptin Benzoate

苯甲酸阿格列汀,SYR 322,Alogliptin(SYR-322)benzoate

Ferroptosis; Proteasome; DPP-4 Apoptosis; Proteases/Proteasome; Ubiquitination
Alogliptin Benzoate (SYR 322) 是一种有效且特异性的 DPP-4 抑制剂 ,IC50值小于 10 nM,其选择性比 DPP-8/9 高 10,000 倍以上,可用于研究 2 型糖尿病。
T6203 Saxagliptin

BMS-477118,沙克列汀,Onglyza,沙格列汀

Proteasome; DPP-4 Proteases/Proteasome; Ubiquitination
Saxagliptin (BMS-477118) 是一种选择性,可逆性,竞争性和口服活性的二肽基肽酶 4 (DPP-4) (Ki= 0.6-1.3 nM) 抑制剂。Saxagliptin 能够用于 2 型糖尿病的研究。
T0178 Saxagliptin hydrate

沙格列汀单水化合物,Onglyza hydrate,BMS-477118 hydrate

Proteasome; DPP-4 Proteases/Proteasome; Ubiquitination
Saxagliptin hydrate (Onglyza hydrate) 是一种选择性,竞争性,可逆性和口服活性的二肽基肽酶 4 (DPP-4) (Ki= 0.6-1.3 nM) 抑制剂。Saxagliptin hydrate 能够用于 2 型糖尿病的研究。
T29019 TS-021

TS021,TS 021,TS-021 Free

DPP-4 Proteases/Proteasome
TS-021 是一种具有选择性的二肽基肽酶 4 (DPP-4) 抑制剂,具有抗糖尿病活性,可用于研究2 型糖尿病。
T7369 Gemigliptin

吉格列汀酒石酸盐,LC15-0444

Proteasome; DPP-4 Proteases/Proteasome; Ubiquitination
Gemigliptin (LC15-0444) 是一种选择性的,可逆的,竞争性的二肽基肽酶 4 (DPP-4) 抑制剂,对人重组 DPP-4 的 IC50=10.3 nM。Gemigliptin 具有很强的抗糖基化活性,能够用于晚期糖基化终产物相关的糖尿病并发症的研究。
T23358 Sitagliptin phosphate

磷酸西他列汀,Januvia,MK-0431 phosphate,Sitagliptin (phosphate)

DPP-4; Autophagy Autophagy; Proteases/Proteasome
Sitagliptin phosphate (MK-0431 phosphate) 是一种二肽基肽酶 4 (DPP4) 抑制剂,在 Caco-2 细胞中,IC50值为 19 nM。
T0191 Linagliptin

BI 1356,利格列汀,利拉利汀

Ferroptosis; Proteasome; DPP-4; Autophagy Apoptosis; Autophagy; Proteases/Proteasome; Ubiquitination
Linagliptin (BI 1356) 是一种有效的、可口服的、基于二氢嘌呤二酮的二肽基肽酶 4 抑制剂,具有降血糖活性。
T2296 Trelagliptin succinate

曲格列汀琥珀酸盐,琥珀酸曲格列汀,SYR-472 succinate,SYR472

Proteasome; DPP-4 Proteases/Proteasome; Ubiquitination
Trelagliptin succinate (SYR-472 succinate) 是一种有效的,具有口服活性的DPP-4抑制剂,IC50=4 nM。它可以改善体内血糖控制,能够用于2 型糖尿病(T2DM) 的研究。
T6999 Teneligliptin hydrobromide

Teneligliptin hydrobromide anhydrous,MP-513 (hydrobromide)

Others; Proteasome; DPP-4 Others; Proteases/Proteasome; Ubiquitination
Teneligliptin hydrobromide (MP-513(hydrobromide)) 是β2肾上腺素能受体 (β2AR) 阻滞剂,具有抗高血压、抗氧化、清除自由基的活性。
T68053 Denagliptin

GW823093

DPP-4 Proteases/Proteasome
Denagliptin是一种小分子二肽基肽酶IV(DPP-4)抑制剂,可用于治疗内分泌于代谢疾病,可用于研究2型糖尿病。
T1502 Vildagliptin

维达列汀,NVP-LAF 237,维格列汀,LAF237

Apoptosis; Ferroptosis; Proteasome; DPP-4 Apoptosis; Proteases/Proteasome; Ubiquitination
Vildagliptin (LAF237) 是一种选择性二肽基肽酶IV (DPP-IV) 抑制剂,在人 Caco-2 细胞中抑制 DPP-IV 的IC50为 3.5 nM。它具有出色的口服生物利用度和降血糖活性。
T0242 Sitagliptin

西他列汀,MK0431,西格列汀

Proteasome; DPP-4; Autophagy Autophagy; Proteases/Proteasome; Ubiquitination
Sitagliptin (MK0431) 是一种有效的 DPP4抑制剂,在 Caco-2 细胞中,IC50值为 19 nM。它是一种新型口服降糖药,可单独使用或与二甲双胍或噻唑烷二酮联合用于治疗 2 型糖尿病。
T30166 ASP-4000 HCl

ASP4000 HCl,ASP 4000 HCl,UNII-7393JFE67B

ASP-4000 HCl is an inhibitor of dipeptidyl peptidase 4 (DPP) with anti-hyperglycemic activity.
T26941 Camegliptin

RO-4876904-001,R1579,RG1579,RO-4876904,R-1579,RG-1579

Cameglipti, a dipeptidyl peptidase IV (DPP-4) inhibitor, is used potentially for the treatment of type 2 diabetes.
T68561 ASP-4000 free base

ASP-4000 free base is a dipeptidyl peptidase 4 (DPP) inhibitor with antihyperglycemic activity.
T27598 Imigliptin Dihydrochloride

Imigliptin

Imigliptin Dihydrochloride, a selective dipeptidyl peptidase IV (DPP-4) inhibitor, is used potentially for the treatment of type II diabetes.
T11248 Evogliptin tartrate

DA-1229 tartrate

DPP-4 Proteases/Proteasome
Evogliptin tartrate has potential for anti-atherosclerosis therapy that targets arterial inflammation. Evogliptin tartrate is a potent, orally bioavailable and selective dipeptidyl peptidase-4 (DPP-4) inhibitor, with antidiabetic activity.
T74592 Sitagliptin fenilalanil hydrochloride

Sitagliptin fenilalanil hydrochloride 是一种二肽氨基肽酶 (DPP-4) 抑制剂。
T68652 Carmegliptin dihydrochloride

Carmegliptin dihydrochloride is the salt form of Camegliptin (free base), also known as RG-1579 and RO4876904, a dipeptidyl peptidase IV (DPP-4) inhibitor potentially for the treatment of type 2 diabetes.
T6203L Saxagliptin hydrochloride

BMS477118,Saxagliptin,BMS 477118,Saxagliptin HCl,BMS-477118

Saxagliptin is a new oral hypoglycemic of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Saxagliptin is a competitive DPP4 inhibitor that slows the inactivation of the incretin hormones and reducing fasting and postprandial glucose conce
T68863 MK-0626 free base

MK-0626 is a Dipeptidyl peptidase IV (DPP-4) inhibitor, improving neovascularization by increasing both the number of circulating endothelial progenitor cells and endothelial nitric oxide synthetase expression.
T35637 Sitagliptin N-Sulfate (sodium salt)

Sitagliptin N-sulfate is a phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin . Sitagliptin N-sulfate is formed via sulfation and has been found in rat bile following oral administration of (-)-sitagliptin.
T35440 (-)-Sitagliptin Carbamoyl Glucuronide

(-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin . (-)-Sitagliptin carbamoyl glucuronide is formed by N-carbamoyl glucuronidation and has been found in rat and dog plasma following administration of (-)-sitagliptin.
T35815 Vildagliptin carboxylic acid metabolite (trifluoroacetate salt)

Vildagliptin carboxylic acid metabolite is the major metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor vildagliptin in humans. Vildagliptin carboxylic acid metabolite has an IC50 value of 477 μM for DPP-4 in human Caco-2 cells. It is formed from hydrolysis of the cyano group on vildagliptin.
T31732 Evogliptin HCl

Evogliptin hydrochloride,DA 1229,DA1229,Evogliptin,DA-1229

Evogliptin(DA-1229) is a potent and selective DPP4 inhibitor (dipeptidyl peptidase 4 inhibitor) that can improve insulin resistance and delays the onset of diabetes. Evogliptin delays the onset of diabetes in young db/db mice and improves insulin sensitiv
T61422 DPP-4-IN-1

DPP-4-IN-1 (compound d1) is a highly potent inhibitor of DPP-4 (dipeptidyl peptidase 4) with an IC 50 of 49 nM, making it suitable for diabetes research [1]. It shares structural similarities to Alogliptin and can be effectively utilized for studying diabetes-related mechanisms.
T61414 DPP-4 inhibitor 3

DPP-4 inhibitor 3 (Compound 5a) 是一种有效的二肽基肽酶 IV (DPP-IV) 抑制剂,IC50为 0.75 nM。DPP-4 inhibitor 3 具有极好的抗氧化和胰岛素性活性。
T63964 DPP-4/GPR119 modulator 2

DPP-4/GPR119 modulator 2 是二肽基肽酶 IV (DPP-IV) 抑制剂 (IC50: 0.22 μM),也是一种 GPR119 激动剂 (EC50: 0.95 μM)。DPP-4/GPR119 modulator 2 能够用于研究糖尿病。
T61018 DPP-4-IN-2

DPP-4-IN-2 (compound b2) 是 Alogliptin 的结构类似物,可以用于研究糖尿病。DPP-4-IN-2 是二肽基肽酶 4 (DPP-4)的有效抑制剂,IC50值为 79 nM。
T36943 Aminopeptidase N Inhibitor

Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 μM). It is selective for AP-N/CD13 over matrix metalloproteinase-9 (MMP-9), angiotensin converting enzyme (ACE), neutral endopeptidase (NEP), γ-glutamyl transpeptidase, and the serine proteases dipeptidyl peptidase 4 (DPP-4) and cathepsin G at a concentration of 1 mM. AP-N inhibitor is non-cytotoxic to U937 cells at a concentration of 100 μM.
T62213 Anagliptin hydrochloride

Anagliptin (SK-0403) hydrochloride 是一种有效的、高度选择性的、口服具有活力的二肽酰肽酶 4 (DPP-4) 抑制剂 (IC50: 3.8 nM),对 DPP-8 (IC50: 68 nM) 和 DDP-9 (IC50: 60 nM) 的选择性相对较弱。
T73875 Fotagliptin benzoate

Fotagliptin benzoate,作为一种二肽基肽酶IV (DPP-4) 抑制剂(IC50=2.27 nM),在大鼠和狗中展现了安全性,适用于2型糖尿病的研究。
T74528 DPP-4/GPR119 modulator 1

DPP-4/GPR119 modulator 1 (Compound 22) 是一种具有口服活性的二肽基肽酶 IV (DPP-IV) 抑制剂和 GPR119激动剂。DPP-4/GPR119 modulator 1 具有降血糖作用,抑制hERG 通道,IC50值为 4.9 µM。DPP-4/GPR119 modulator 1 可用于糖尿病的研究。
T79256 DPP-4-IN-8

DPP-4-IN-8 (compound 27) 是一种高效的选择性DPP4抑制剂,具有 0.96 μM 的 Ki。该化合物能够抑制 Caco-2 和 HepG-2 细胞中的 DPP4 二肽酶活性,并剂量依赖性地降低 TNF-α、IL-6 和 IL-1β 的表达水平[1]。
T37861 Talabostat

Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM. Talabostat is a nonselective DPP-IV inhibitor, inhibiting DPP8/9, FAP, DPP2 and some other DASH family enzymes essentially as potently as it inhibits DPP-IV[1]. Talabostat stimulates the immune system by triggering a proinflammatory form of cell death in monocytes and macrophages known as pyroptosis. The inhibition of two serine proteases, DPP8 and DPP9,...
T37522 Teneligliptin

Teneligliptin (MP-513) is a potent chemotype prolylthiazolidine-based DPP-4 inhibitor, which competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50s of approximately 1 nM. Teneligliptin (MP-513) inhibits all these DPP-4 enzymes in a concentration-dependent manner. The IC50s of Teneligliptin (MP-513) for rhDPP-4, human plasma, and rat plasma are 0.889, 1.75, and 1.35 nM, respectively. A study of enzyme inhibition kinetics is conducted for Teneligliptin (M...

化合物

DPP-IV-IN-2
Cat.No: T11526
Synonym: H-Lys(4-nitro-Z)-pyrrolidide
Target: DPP-4
Alogliptin
Cat.No: T6192
Synonym: SYR-322,阿格列汀,阿洛利停
Target: Ferroptosis, Proteasome, DPP-4
Gemigliptin Tartrate(911637-19-9 free base)
Cat.No: T7369L
Synonym: 吉格列汀酒石酸盐,LC15-0444 tartrate
Target: Proteasome, DPP-4
Retagliptin Phosphate
Cat.No: T12710
Synonym: SP 2086,瑞格列汀磷酸盐
Target: Proteasome, DPP-4
Anagliptin
Cat.No: T7133
Synonym: SK-0403,阿拉格列汀
Target: Proteasome, DPP-4
Alogliptin Benzoate
Cat.No: T2401
Synonym: 苯甲酸阿格列汀,SYR 322,Alogliptin(SYR-322)benzoate
Target: Ferroptosis, Proteasome, DPP-4
Saxagliptin
Cat.No: T6203
Synonym: BMS-477118,沙克列汀,Onglyza,沙格列汀
Target: Proteasome, DPP-4
Saxagliptin hydrate
Cat.No: T0178
Synonym: 沙格列汀单水化合物,Onglyza hydrate,BMS-477118 hydrate
Target: Proteasome, DPP-4
TS-021
Cat.No: T29019
Synonym: TS021,TS 021,TS-021 Free
Target: DPP-4
Gemigliptin
Cat.No: T7369
Synonym: 吉格列汀酒石酸盐,LC15-0444
Target: Proteasome, DPP-4
Sitagliptin phosphate
Cat.No: T23358
Synonym: 磷酸西他列汀,Januvia,MK-0431 phosphate,Sitagliptin (phosphate)
Target: DPP-4, Autophagy
Linagliptin
Cat.No: T0191
Synonym: BI 1356,利格列汀,利拉利汀
Target: Ferroptosis, Proteasome, DPP-4, Autophagy
Trelagliptin succinate
Cat.No: T2296
Synonym: 曲格列汀琥珀酸盐,琥珀酸曲格列汀,SYR-472 succinate,SYR472
Target: Proteasome, DPP-4
Teneligliptin hydrobromide
Cat.No: T6999
Synonym: Teneligliptin hydrobromide anhydrous,MP-513 (hydrobromide)
Target: Others, Proteasome, DPP-4
Denagliptin
Cat.No: T68053
Synonym: GW823093
Target: DPP-4
Vildagliptin
Cat.No: T1502
Synonym: 维达列汀,NVP-LAF 237,维格列汀,LAF237
Target: Apoptosis, Ferroptosis, Proteasome, DPP-4
Sitagliptin
Cat.No: T0242
Synonym: 西他列汀,MK0431,西格列汀
Target: Proteasome, DPP-4, Autophagy
ASP-4000 HCl
Cat.No: T30166
Synonym: ASP4000 HCl,ASP 4000 HCl,UNII-7393JFE67B
Target:
Camegliptin
Cat.No: T26941
Synonym: RO-4876904-001,R1579,RG1579,RO-4876904,R-1579,RG-1579
Target:
ASP-4000 free base
Cat.No: T68561
Synonym:
Target:
Imigliptin Dihydrochloride
Cat.No: T27598
Synonym: Imigliptin
Target:
Evogliptin tartrate
Cat.No: T11248
Synonym: DA-1229 tartrate
Target: DPP-4
Sitagliptin fenilalanil hydrochloride
Cat.No: T74592
Synonym:
Target:
Carmegliptin dihydrochloride
Cat.No: T68652
Synonym:
Target:
Saxagliptin hydrochloride
Cat.No: T6203L
Synonym: BMS477118,Saxagliptin,BMS 477118,Saxagliptin HCl,BMS-477118
Target:
MK-0626 free base
Cat.No: T68863
Synonym:
Target:
Sitagliptin N-Sulfate (sodium salt)
Cat.No: T35637
Synonym:
Target:
(-)-Sitagliptin Carbamoyl Glucuronide
Cat.No: T35440
Synonym:
Target:
Vildagliptin carboxylic acid metabolite (trifluoroacetate salt)
Cat.No: T35815
Synonym:
Target:
Evogliptin HCl
Cat.No: T31732
Synonym: Evogliptin hydrochloride,DA 1229,DA1229,Evogliptin,DA-1229
Target:
DPP-4-IN-1
Cat.No: T61422
Synonym:
Target:
DPP-4 inhibitor 3
Cat.No: T61414
Synonym:
Target:
DPP-4/GPR119 modulator 2
Cat.No: T63964
Synonym:
Target:
DPP-4-IN-2
Cat.No: T61018
Synonym:
Target:
Aminopeptidase N Inhibitor
Cat.No: T36943
Synonym:
Target:
Anagliptin hydrochloride
Cat.No: T62213
Synonym:
Target:
Fotagliptin benzoate
Cat.No: T73875
Synonym:
Target:
DPP-4/GPR119 modulator 1
Cat.No: T74528
Synonym:
Target:
DPP-4-IN-8
Cat.No: T79256
Synonym:
Target:
Talabostat
Cat.No: T37861
Synonym:
Target:
Teneligliptin
Cat.No: T37522
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TN1418 Azaleatin

杜鹃黄素,2-(3,4-二羟基苯基)-3,7-二羟基-5-甲氧基苯并吡喃-4-酮

DPP-4 Proteases/Proteasome
Azaleatin 是分离自Rhododendron 种中的 O-甲基化黄酮醇。它是二肽基肽酶-IV 的抑制剂。它在 2 型糖尿病和肥胖症中有研究的价值。
T16838 Saikogenin A

Proteasome; DPP-4 Proteases/Proteasome; Ubiquitination
Saikogenin A 是一种二肽基肽酶 IV 抑制剂,可从中药柴胡中提取。

天然产物

Azaleatin
Cat.No: TN1418
Synonym: 杜鹃黄素,2-(3,4-二羟基苯基)-3,7-二羟基-5-甲氧基苯并吡喃-4-酮
Target: DPP-4
Saikogenin A
Cat.No: T16838
Synonym:
Target: Proteasome, DPP-4
Cat. No. Product Name Species Expression System
TMPY-02731 SPINK4 Protein, Mouse, Recombinant (hFc)

MPGC60,serine peptidase inhibitor, Kazal t...

Mouse HEK293 Cells
SPINK4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.5 kDa and the accession number is O35679.
TMPJ-00931 Serpin A4 Protein, Human, Recombinant (His)

Kallistatin,Peptidase Inhibitor 4...

Human HEK293 Cells
Serpin Peptidase Inhibitor, Clade A (α-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and secreted in plasma. Serpin A4 is a regulator of vascular homeostasis capable of controlling a wide spectrum of biological actions in the cardiovascular and renal systems. It can inhibit intracellular reactive oxygen species formation in cultured cardiac and renal cells. In addition,...
TMPY-05786 SPINK4 Protein, Mouse, Recombinant (His)

RP23-28I8.2,serine peptidase inhibitor, Ka...

Mouse HEK293 Cells
SPINK4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 8.11 kDa and the accession number is O35679.
TMPY-01454 SPINK4 Protein, Human, Recombinant (His)

MGC133107,PEC-60,HEL136,PEC60,serine peptidase ...

Human HEK293 Cells
SPINK4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 8 kDa and the accession number is O60575.
TMPY-00623 Serpin A1d Protein, Mouse, Recombinant

PI4,serine (or cysteine) peptidase inh...

Mouse HEK293 Cells
Serpin A1d Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 44.1 kDa and the accession number is XP_003945711.1.
TMPY-00621 Serpin A1d Protein, Mouse, Recombinant (His)

AI118301,Serpin A1d,Spi1-4,PI4,Dom4

Mouse HEK293 Cells
Serpin A1d Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.9 kDa and the accession number is XP_003945711.1.
TMPY-00619 Serpin A1d Protein, Mouse, Recombinant (hFc)

Spi1-4,PI4,Serpin A1d,serine (or cysteine)...

Mouse HEK293 Cells
Serpin A1d Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.2 kDa and the accession number is XP_003945711.1.
TMPJ-01083 Serpin E2 Protein, Mouse, Recombinant (His)

Pi7,Protease nexin I,Spi4,Pn1,Serine protease-i...

Mouse HEK293 Cells
Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice leads to progressive neuronal and motor dysfunction in these animals. It is also over-expressed in the majority of pancreatic carcinoma as well as gastric and colorectal cancer samples whereas it is weakly expressed in all normal pancreas and chronic pancreatitis tissue samples. Ser...
TMPY-02425 Serpin B4, Protein, Human, Recombinant (His)

SCCA-2,LEUPIN,SCCA1,serpin peptidase inhibitor<...

Human Baculovirus Insect Cells
Overexpression of SERPINB4 in tumor cells inhibited recombinant GrM-induced as well as NK cell-mediated cell death and this inhibition depended on the reactive center loop of the serpin.
TMPJ-01320 BSSP-4 Protein, Human, Recombinant (His)

BSSP4,Tryptase ε,Serine Protease 26,BSSP-4...

Human HEK293 Cells
Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung, but scarce in adult lung and expressed at low levels in placenta, pancreas, prostate and thyroid gland. BSSP-4 belongs to the peptidase S1 family and related to trypsin, referentially hydrolyzing substrates after a...
TMPY-00749 FGF-2 Protein, Human, Recombinant

fibroblast growth factor 2 (basic),FGF-2,FGFB,HBGF-2,BFGF

Human E. coli
FGF-2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.5 kDa and the accession number is P09038-4.
TMPJ-00864 VEGF165 Protein, Human, Recombinant

Vascular Endothelial Growth Factor Isoform 165,血管内皮生长因子,VEGF...

Human HEK293 Cells
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms, of which VEGF165 is the most abundant one. VEGF165 is a disulfide-linked homodimer consisting of two glycosylated 165 amino acid polypeptide chains. VEGF stimul...
TMPK-00823 VEGF165 Protein, Human, Recombinant (His & Avi)

血管内皮生长因子,RP1-261G23.1,MVCD1,MGC70609,VEGFA,VEGFMGC70609,VPF,...

Human HEK293 Cells
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF165 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.2 kDa and the accession number is P15692-4.
TMPY-04911 VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated

vascular endothelial growth factor A,血管内皮生长因子

Human,Cynomolgus HEK293 Cells
VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.1 kDa and the accession number is P15692-4.
TMPY-02893 NT5C3A/NT5C3 Protein, Human, Recombinant

P5N1,P5N-1,hUMP1,NT5C3,cN-III,PSN1,UMPH1,UMPH,POMP,5'-nucleo...

Human E. coli
NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. NT5C3A expression required both an intronic IFN-stimulated response element and the IFN-stimulated transcription factor IRF1. Overexpression of NT5C3A, but...
TMPK-00424 CD45 Protein, Human, Recombinant (His & Avi), Biotinylated

LCA,LY5,EC 3.1.3.48,CD45,L-CA,T200,CD4...

Human HEK293 Cells
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. CD45 Protein, Human, Recombinant (His & Avi...
TMPK-00822 VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled

RP1-261G23.1,VEGFA,MGC70609,VEGF,VEGFMGC70609,VPF,VAS,MVCD1,...

Human HEK293 Cells
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.2 kDa and the accession number is P15692-4.
TMPY-04471 APEG1 Protein, Human, Recombinant (His)

SPEG complex locus,BPEG,SPEGalpha,SPEGβ,APEG-1,SPEGbeta,APEG...

Human E. coli
Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein that belongs to the protein kinase superfamily and CAMK Ser/Thr protein kinase family. SPEG / APEG-1 contains two fibronectin type-III domains, nine Ig-like (immunoglobulin-like) domains, two protein kinase domains. Isoform 1 of SPEG is preferentially expressed in striated muscle. Non-kinase form such as isoform 3 of SPEG is predominantly expre...
TMPK-00423 CD45 Protein, Human, Recombinant (His & Avi)

CD45R,LY5,EC 3.1.3.48,B220,CD45,T...

Human HEK293 Cells
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. CD45 Protein, Human, Recombinant (His & Avi...
TMPJ-01333 TEM8/ANTXR1 Protein, Human, Recombinant (His)

ATR,ANTXR1,TEM8,Tumor Endothelial Marker 8,Anthrax Toxin Rec...

Human HEK293 Cells
Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It ...
TMPY-05598 Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated

SIGLEC2,SIGLEC-2,CD22 molecule

Human HEK293 Cells
Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 103.7 kDa and the accession number is P20273-4.
TMPJ-00782 Amyloid Precursor Protein, Human, Recombinant (hFc)

Amyloid Precursor,Amyloid Precursor Protein 695,APP695

Human HEK293 Cells
Amyloid precursor protein (APP) is a type I membrane protein with several isoforms due to alternative splicing, performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Of the three major splice isoforms of APP (APP695, APP751, and APP770) APP695 is the predominant neuronal form from which Amyloid beta peptide and transcriptionally-active cleaved intracellular domain of APP (AICD) are preferentially generated by selective process...
TMPY-04754 CASK Protein, Human, Recombinant

CMG,LIN2,MRXSNA,CAMGUK,calcium/calmodulin-dependent serine p...

Human Baculovirus Insect Cells
CASK Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 102.1 kDa and the accession number is O14936-4.
TMPY-00225 CLEC9A Protein, Mouse, Recombinant (hFc)

C-type lectin domain family 9, member A,9830005G06Rik,DNGR-1

Mouse HEK293 Cells
CLEC9A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.1 kDa and the accession number is Q8BRU4-4.
TMPY-01117 MRAP Protein, Human, Recombinant (hFc)

FALP,FGD2,melanocortin 2 receptor accessory protein,GCCD2,B2...

Human HEK293 Cells
MRAP (Melanocortin 2 Receptor Accessory Protein) is a Protein Coding gene. This gene encodes a melanocortin receptor-interacting protein. It belongs to the MRAP family. MRAP, which contains a single transmembrane domain, has a unique structure, an antiparallel homodimer. MRAP is a single transmembrane domain accessory protein and a critical component of the hypothamo pituitary-adrenal axis. MRAP is highly expressed in the adrenal gland and is essential for adrenocorticotropin hormone (ACTH) rece...
TMPJ-00233 CD200R1/CRTR2 Protein, Human, Recombinant (His)

Cell Surface Glycoprotein CD200 Receptor 1,OX2R,MOX2R,CD200 ...

Human HEK293 Cells
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytopla...
TMPK-00702 ANTXR2 Protein, Human, Recombinant (His)

cI-35,Antxr2,JHS,CMG-2,CMG2,JHF,HFS,ISH

Human HEK293 Cells
The Capillary Morphogenesis Gene 2 (CMG2) gene encodes an Anthrax toxin receptor (ANTXR2),ANTXR2/CMG2 was originally identified as a result of up-regulation during capillary morphogenesis of endothelial cells (ECs) cultured in vitro. ANTXR2/CMG2 functions to promote endothelial proliferation and morphogenesis during sprouting angiogenesis, consistent with the endothelial expression of ANTXR2/CMG2 in several vascular beds.
TMPY-01033 IL-32 Protein, Human, Recombinant (isoform alpha, His)

IL-32δ,IL-32beta,IL32,TAIFc,IL-32γ,白介素,IL-32 Protein(isoform...

Human HEK293 Cells
IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma, and delta) are the most representative IL-32 transcripts, and the gamma isoform of IL-32 is the most active,...
TMPY-01823 PTK9 Protein, Human, Recombinant

MGC41876,twinfilin actin binding protein 1,A6,MGC23...

Human E. coli
PTK9 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 29 kDa and the accession number is Q12792-4.
TMPY-00119 FLT1 Protein, Human, Recombinant (hFc)

VEGFR1,VEGFR-1,fms-related tyrosine kinase 1,FLT-1,FLT

Human HEK293 Cells
FLT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.1 kDa and the accession number is P17948-4.
TMPY-04563 CASK Protein, Human, Recombinant (His & GST)

calcium/calmodulin-dependent serine protein kinase (MAGUK fa...

Human Baculovirus Insect Cells
CASK Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 130 kDa and the accession number is O14936-4.
TMPJ-01256 Caspase-10 Protein, Human, Recombinant (His)

CASP10,FAS-Associated Death Domain Protein Interleukin-1B-Co...

Human E. coli
Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granzyme B and autocatalytic activity generate the two active subunits: Caspase-10 subunit p23/17, Caspase-10 subunit p12. Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the execution-phase of cell apoptosis, the initiation and execution. Human ca...
TMPY-01822 PTK9 Protein, Human, Recombinant (His & GST)

PTK9,MGC41876,A6,MGC23788,twinfilin actin binding p...

Human E. coli
PTK9 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 57 kDa and the accession number is Q12792-4.
TMPY-04565 SRPK3 Protein, Human, Recombinant (His & GST)

MSSK1,MGC102944,STK23,MSSK-1,SRSF protein ...

Human Baculovirus Insect Cells
Serine / threonine-protein kinase SRPK3, also known as Muscle-specific serine kinase 1, Serine/arginine-rich protein-specific kinase 3, SR-protein-specific kinase 3, Serine / threonine-protein kinase 23, MSSK-1, SRPK3 and MSSK1, is a member of the protein kinase superfamily and CMGC Ser / Thr protein kinase family. SRPK3 is a protein kinase belonging to serine/arginine protein kinases (SRPK) family, which phosphorylates serine / arginine repeat-containing proteins, and is controlled by a muscle-...
TMPJ-01188 CORO6 Protein, Human, Recombinant (His)

Coronin-6,Clipin-E,CORO6

Human E. coli
Coronin 6, a newly identified member of the coronin family, is highly enriched at adult NMJs and regulates AChR clustering via modulating the interaction between receptors and the actin cytoskeletal network. Coronins are a family of conserved actin-binding proteins originally identified in the actin-rich structure of the amoeba Dictyostelium discoideum . To date, seven members of coronins have been identified in mammals, and most exhibit tissue-specific distribution patterns. Coronin 6 is promin...
TMPY-01933 CHI3L2 Protein, Human, Recombinant (His)

YKL-39,CHIL2,chitinase 3 like 2,YKL39

Human HEK293 Cells
Chondrocyte protein 39 (YKL-39), also known as Chitinase 3-like 2 (CHI3L2), is a secretory protein of articular chondrocytes belonging to the glycosyl hydrolase 18 family. Its highest expression is in chondrocytes, followed by synoviocytes, lung and heart. YKL-39/CHI3L2 is not detected in spleen, pancreas, and liver. YKL-39/CHI3L2 may also be expressed in developing brain and placenta. YKL-39/CHI3L2, a cartilage-related protein, is found to induce arthritis accompanied by pathologic changes in b...
TMPJ-00410 CD45R0 Protein, Human, Recombinant (His)

CD45 antigen,L-CA,protein tyrosine phosphatase, rec...

Human HEK293 Cells
CD45R0 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 80-120 KDa and the accession number is P08575-4.
TMPY-00711 CD45 Protein, Human, Recombinant (hFc)

GP180,L-CA,LY5,T200,protein tyrosine phosphatase, receptor t...

Human HEK293 Cells
CD45 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.1 kDa and the accession number is P08575-4.
TMPY-00380 ANTXR2 Protein, Human, Recombinant (hFc)

HFS,JHF,anthrax toxin receptor 2,ISH,CMG-2,CMG2

Human HEK293 Cells
ANTXR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.4 kDa and the accession number is P58335-4.
TMPK-01362 SIRP alpha V4 Protein, Human, Recombinant (His & Avi), Biotinylated

MYD1,SIRP α V4,PTPNS1,BIT,SHPS1,SIRP alpha,SHPS-1,S...

Human HEK293 Cells
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c...
TMPK-01356 SIRP alpha V4 Protein, Human, Recombinant (His & Avi)

BIT,SIRP α V4,MFR,SHPS1,SIRPA,SIRP α,P84,M...

Human HEK293 Cells
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi...

重组蛋白

SPINK4 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02731
Species: Mouse
Expression System: HEK293 Cells
Serpin A4 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00931
Species: Human
Expression System: HEK293 Cells
SPINK4 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05786
Species: Mouse
Expression System: HEK293 Cells
SPINK4 Protein, Human, Recombinant (His)
Cat.No: TMPY-01454
Species: Human
Expression System: HEK293 Cells
Serpin A1d Protein, Mouse, Recombinant
Cat.No: TMPY-00623
Species: Mouse
Expression System: HEK293 Cells
Serpin A1d Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00621
Species: Mouse
Expression System: HEK293 Cells
Serpin A1d Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-00619
Species: Mouse
Expression System: HEK293 Cells
Serpin E2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01083
Species: Mouse
Expression System: HEK293 Cells
Serpin B4, Protein, Human, Recombinant (His)
Cat.No: TMPY-02425
Species: Human
Expression System: Baculovirus Insect Cells
BSSP-4 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01320
Species: Human
Expression System: HEK293 Cells
FGF-2 Protein, Human, Recombinant
Cat.No: TMPY-00749
Species: Human
Expression System: E. coli
VEGF165 Protein, Human, Recombinant
Cat.No: TMPJ-00864
Species: Human
Expression System: HEK293 Cells
VEGF165 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00823
Species: Human
Expression System: HEK293 Cells
VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-04911
Species: Human,Cynomolgus
Expression System: HEK293 Cells
NT5C3A/NT5C3 Protein, Human, Recombinant
Cat.No: TMPY-02893
Species: Human
Expression System: E. coli
CD45 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00424
Species: Human
Expression System: HEK293 Cells
VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled
Cat.No: TMPK-00822
Species: Human
Expression System: HEK293 Cells
APEG1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04471
Species: Human
Expression System: E. coli
CD45 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00423
Species: Human
Expression System: HEK293 Cells
TEM8/ANTXR1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01333
Species: Human
Expression System: HEK293 Cells
Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-05598
Species: Human
Expression System: HEK293 Cells
Amyloid Precursor Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00782
Species: Human
Expression System: HEK293 Cells
CASK Protein, Human, Recombinant
Cat.No: TMPY-04754
Species: Human
Expression System: Baculovirus Insect Cells
CLEC9A Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-00225
Species: Mouse
Expression System: HEK293 Cells
MRAP Protein, Human, Recombinant (hFc)
Cat.No: TMPY-01117
Species: Human
Expression System: HEK293 Cells
CD200R1/CRTR2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00233
Species: Human
Expression System: HEK293 Cells
ANTXR2 Protein, Human, Recombinant (His)
Cat.No: TMPK-00702
Species: Human
Expression System: HEK293 Cells
IL-32 Protein, Human, Recombinant (isoform alpha, His)
Cat.No: TMPY-01033
Species: Human
Expression System: HEK293 Cells
PTK9 Protein, Human, Recombinant
Cat.No: TMPY-01823
Species: Human
Expression System: E. coli
FLT1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00119
Species: Human
Expression System: HEK293 Cells
CASK Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04563
Species: Human
Expression System: Baculovirus Insect Cells
Caspase-10 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01256
Species: Human
Expression System: E. coli
PTK9 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-01822
Species: Human
Expression System: E. coli
SRPK3 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04565
Species: Human
Expression System: Baculovirus Insect Cells
CORO6 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01188
Species: Human
Expression System: E. coli
CHI3L2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01933
Species: Human
Expression System: HEK293 Cells
CD45R0 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00410
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00711
Species: Human
Expression System: HEK293 Cells
ANTXR2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00380
Species: Human
Expression System: HEK293 Cells
SIRP alpha V4 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-01362
Species: Human
Expression System: HEK293 Cells
SIRP alpha V4 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-01356
Species: Human
Expression System: HEK293 Cells
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